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Single‐Cell Tracking: A New Microengineered Platform for 4D Tracking of Single Cells in a Stem‐Cell‐Based In Vitro Morphogenesis Model (Adv. Mater. 24/2020)
Author(s) -
Samal Pinak,
Maurer Philipp,
Blitterswijk Clemens,
Truckenmüller Roman,
Giselbrecht Stefan
Publication year - 2020
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.202070182
Subject(s) - materials science , morphogenesis , nanotechnology , stem cell , cell , tracking (education) , pipeline (software) , microbiology and biotechnology , biomedical engineering , computer science , biology , engineering , biochemistry , psychology , pedagogy , gene , programming language
In article number 1907966, Stefan Giselbrecht and co‐workers describe a new multifunctional microengineered platform to study patterning in free‐floating 3D stem cell aggregates. The platform synergistically combines controlled 3D cell culture in tailored microwells with an open‐source image analysis pipeline to track real‐time aggregate morphogenesis at cellular resolution.