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Cancer Immunotherapy: Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy (Adv. Mater. 16/2020)
Author(s) -
Um Wooram,
Ko Hyewon,
You Dong Gil,
Lim Seungho,
Kwak Gijung,
Shim Man Kyu,
Yang Suah,
Lee Jeongjin,
Song Yeari,
Kim Kwangmeyung,
Park Jae Hyung
Publication year - 2020
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.202070121
Subject(s) - necroptosis , immunotherapy , cancer immunotherapy , cancer , materials science , immune system , cancer research , cancer cell , nanotechnology , programmed cell death , biology , immunology , medicine , apoptosis , biochemistry
In article number 1907953, Jae Hyung Park and co‐workers present the potential of necroptosis‐inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage‐associated molecular patterns and tumor‐associated antigens by inducing cell membrane rupture, facilitating efficient maturation of the dendritic cell for antitumor immune response.