Premium
Functional Micro‐/Nanomaterials for Multiplexed Biodetection
Author(s) -
Liu Xinyi,
Wu Weijie,
Cui Daxiang,
Chen Xiaoyuan,
Li Wanwan
Publication year - 2021
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.202004734
Subject(s) - nanotechnology , multiplexing , nanomaterials , materials science , human health , biochemical engineering , computer science , engineering , telecommunications , medicine , environmental health
When analyzing biological phenomena and processes, multiplexed biodetection has many advantages over single‐factor biodetection and is highly relevant to both human health issues and advancements in the life sciences. However, many key problems with current multiplexed biodetection strategies remain unresolved. Herein, the main issues are analyzed and summarized: 1) generating sufficient signal to label targets, 2) improving the signal‐to‐noise ratio to ensure total detection sensitivity, and 3) simplifying the detection process to reduce the time and labor costs of multiple target detection. Then, available solutions made possible by designing and controlling the properties of micro‐ and nanomaterials are introduced. The aim is to emphasize the role that micro‐/nanomaterials can play in the improvement of multiplexed biodetection strategies. Through analyzing existing problems, introducing state‐of‐the‐art developments regarding relevant materials, and discussing future directions of the field, it is hopeful to help promote necessary developments in multiplexed biodetection and associated scientific research.