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Cancer Immunotherapy: Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure (Adv. Mater. 52/2019)
Author(s) -
Chen Chao,
Ni Xiang,
Jia Shaorui,
Liang Yong,
Wu Xiaoli,
Kong Deling,
Ding Dan
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201970372
Subject(s) - programmed cell death , oxidative stress , photosensitizer , mitochondrion , materials science , immunotherapy , aggregation induced emission , cancer immunotherapy , microbiology and biotechnology , cancer research , biophysics , nanotechnology , apoptosis , biology , immune system , biochemistry , photochemistry , chemistry , immunology , optics , fluorescence , physics
In article number 1904914, Dan Ding and co‐workers demonstrate that focused mitochondrial oxidative stress can massively evoke immunogenic cell death (ICD) in cancer immunotherapy, and that aggregation‐induced emission (AIE) is a desirable platform for developing advanced photosensitizer‐based ICD inducers.