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Self‐Assembly: Programmable Construction of Peptide‐Based Materials in Living Subjects: From Modular Design and Morphological Control to Theranostics (Adv. Mater. 45/2019)
Author(s) -
Li LiLi,
Qiao ZengYing,
Wang Lei,
Wang Hao
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201970321
Subject(s) - modular design , nanotechnology , materials science , drug delivery , in vivo , nanomaterials , computer science , biology , operating system , microbiology and biotechnology
The strategy of “in vivo self‐assembly”, which is defined as in situ construction of functional nanomaterials in living subjects to explore new biological effects, is summarized by Zeng‐Ying Qiao, Lei Wang, Hao Wang, and Li‐Li Li in article number 1804971. The modular design platform automatic senses the targeting physiological microenvironment and constructs defined nanostructures in vivo. These dynamically assembled delivery platforms exhibit the assembly/aggregation‐induced retention (AIR) effect, resulting in an enhanced targeting efficiency, which will further be applied in clinical high‐performance drug delivery and bioimaging.