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Cancer Modeling: 3D‐Bioprinted Mini‐Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics (Adv. Mater. 14/2019)
Author(s) -
Heinrich Marcel Alexander,
Bansal Ruchi,
Lammers Twan,
Zhang Yu Shrike,
Michel Schiffelers Raymond,
Prakash Jai
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201970101
Subject(s) - glioblastoma , brain cancer , immunotherapy , brain tumor , cancer research , cancer , immune system , cancer immunotherapy , neuroscience , materials science , biology , medicine , immunology , pathology
Immune cells such as glioblastoma‐associated macrophages play a crucial role in the progression and invasiveness of glioblastoma multiforme. In article number 1806590 , Marcel Alexander Heinrich, Jai Prakash, and co‐workers describe a novel 3D bioprinted model of glioblastoma multiforme in the form of mini‐brains that allow the study of the specific interaction between these macrophages and tumor cells, as well as the testing of the chemo‐ and immunotherapy in a biologically relevant fashion.