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Drug Delivery: Modular Metal–Organic Polyhedra Superassembly: From Molecular‐Level Design to Targeted Drug Delivery (Adv. Mater. 12/2019)
Author(s) -
Zhu Wei,
Guo Jimin,
Ju Yi,
Serda Rita E.,
Croissant Jonas G.,
Shang Jin,
Coker Eric,
Agola Jacob Ongudi,
Zhong QiZhi,
Ping Yuan,
Caruso Frank,
Brinker C. Jeffrey
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201970082
Subject(s) - drug delivery , nanotechnology , materials science , drug , targeted drug delivery , modular design , combinatorial chemistry , computer science , pharmacology , chemistry , medicine , operating system
A novel and modular super‐assembly approach combines the synergistic advantages of metal–organic cage super‐assemblies (e.g., highly controlled architecture, high payloads of multiple cargos) and micelles (e.g., low inherent toxicity) for targeted drug delivery is presented by Wei Zhu, C. Jeffrey Brinker, and co‐workers in article number 1806774 . By modification of the targeting moieties, targeted drug delivery to cancer cells is realized.