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Personalized Tissue Implants: Personalized Hydrogels for Engineering Diverse Fully Autologous Tissue Implants (Adv. Mater. 1/2019)
Author(s) -
Edri Reuven,
Gal Idan,
Noor Nadav,
Harel Tom,
Fleischer Sharon,
Adadi Nofar,
Green Ori,
Shabat Doron,
Heller Lior,
Shapira Assaf,
GatViks Irit,
Peer Dan,
Dvir Tal
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201970007
Subject(s) - self healing hydrogels , tissue engineering , induced pluripotent stem cell , biomedical engineering , materials science , regenerative medicine , stem cell , medicine , microbiology and biotechnology , biology , embryonic stem cell , biochemistry , polymer chemistry , gene
Personalized hydrogels for engineering patient‐specific tissues are reported by Tal Dvir and co‐workers in article number 1803895 . A small fatty tissue biopsy is taken from the patient by a minimally invasive procedure and the cellular and the a‐cellular materials then separated. While the cells are reprogrammed to become induced pluripotent stem cells (iPSCs), the a‐cellular material is processed into a personalized hydrogel. After re‐integration, it is possible to engineer any tissue type, including spinal cord implants.