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Advances in Biomaterials and Technologies for Vascular Embolization
Author(s) -
Hu Jingjie,
Albadawi Hassan,
Chong Brian W.,
Deipolyi Amy R.,
Sheth Rahul A.,
Khademhosseini Ali,
Oklu Rahmi
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201901071
Subject(s) - embolization , materials science , biomedical engineering , microsphere , biocompatible material , nanotechnology , medicine , radiology , engineering , chemical engineering
Minimally invasive transcatheter embolization is a common nonsurgical procedure in interventional radiology used for the deliberate occlusion of blood vessels for the treatment of diseased or injured vasculature. A wide variety of embolic agents including metallic coils, calibrated microspheres, and liquids are available for clinical practice. Additionally, advances in biomaterials, such as shape‐memory foams, biodegradable polymers, and in situ gelling solutions have led to the development of novel preclinical embolic agents. The aim here is to provide a comprehensive overview of current and emerging technologies in endovascular embolization with respect to devices, materials, mechanisms, and design guidelines. Limitations and challenges in embolic materials are also discussed to promote advancement in the field.