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Artificial Organelles: Nanomaterial‐Based Organelles Protect Normal Cells against Chemotherapy‐Induced Cytotoxicity (Adv. Mater. 27/2018)
Author(s) -
Zhao Ruibo,
Liu Xueyao,
Yang Xinyan,
Jin Biao,
Shao Changyu,
Kang Weijia,
Tang Ruikang
Publication year - 2018
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201870202
Subject(s) - organelle , cytoplasm , nanomaterials , materials science , intracellular , nanotechnology , cytotoxicity , biocompatible material , artificial cell , microbiology and biotechnology , chemistry , biology , biomedical engineering , biochemistry , in vitro , membrane , medicine
Parallel to cellular organelles, artificial organelles based on nanomaterials are necessarily responsive to molecular cues and are biocompatible in a molecularly crowded cytoplasm. In article number 1801304 , Ruikang Tang and co‐workers present rationally designed nanomaterials of gold–oligonucleotides, which act as artificial organelles and conferr cell self‐defense in the threatening chemotherapeutic milieu. This intracellular implantation of functional artificial organelles into cells provides a novel and promising tactic for adjusting cell behavior and for manufacturing super cells.