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Cancer Therapy: Virion‐Like Membrane‐Breaking Nanoparticles with Tumor‐Activated Cell‐and‐Tissue Dual‐Penetration Conquer Impermeable Cancer (Adv. Mater. 27/2018)
Author(s) -
Zhang Xiao,
Xu Xianghui,
Li Yachao,
Hu Cheng,
Zhang Zhijun,
Gu Zhongwei
Publication year - 2018
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201870199
Subject(s) - materials science , penetration (warfare) , cancer cell , cancer , nanoparticle , cancer therapy , cell , nanotechnology , membrane , cell membrane , tumor cells , biophysics , cancer research , biology , biochemistry , operations research , engineering , genetics
Virion‐like membrane‐breaking nanoparticles are developed by a bioinspired molecular and supramolecular design for tumor‐activated cell‐and‐tissue dual‐penetration by Xianghui Xu, Zhongwei Gu, and co‐workers in article number 1707240 . The virion‐like nanoparticles can not only directly invade tumor cells, but also penetrate from endothelial/tumor cells into other tumor cells, allowing highly efficient treatment of impermeable and chemotherapy‐resistant cancer. The image was designed by Yachao Li.