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Biomimicry Model: Mechanobiological Mimicry of Helper T Lymphocytes to Evaluate Cell–Biomaterials Crosstalk (Adv. Mater. 23/2018)
Author(s) -
HasaniSadrabadi Mohammad Mahdi,
Majedi Fatemeh S.,
Bensinger Steven J.,
Wu Benjamin M.,
Bouchard LouisS.,
Weiss Paul S.,
Moshaverinia Alireza
Publication year - 2018
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201870159
Subject(s) - crosstalk , materials science , biomimetics , nanotechnology , replica , tissue engineering , self healing hydrogels , biomedical engineering , engineering , visual arts , electronic engineering , polymer chemistry , art
Super‐soft functional microparticles mimic the mechanobiological features of T cells. These particles can penetrate 3D microenvironments, have prolonged blood circulation, and can release various cytokines on demand. A biomimetic model presented by Louis‐S. Bouchard, Paul S. Weiss, Alireza Moshaverinia, and co‐workers in article number 1706780 enables optimization of the design parameters required for the engineering of more efficient drug carriers and serves as a potent replica for understanding the mechanical behavior of immune cells.