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Cancer Therapy: Emerging Strategies of Cancer Therapy Based on Ferroptosis (Adv. Mater. 12/2018)
Author(s) -
Shen Zheyu,
Song Jibin,
Yung Bryant C.,
Zhou Zijian,
Wu Aiguo,
Chen Xiaoyuan
Publication year - 2018
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201870084
Subject(s) - cancer therapy , reactive oxygen species , lipid peroxidation , cancer , endocytosis , materials science , cancer research , nanomaterials , cancer cell , fenton reaction , cancer treatment , nanotechnology , microbiology and biotechnology , biochemistry , medicine , chemistry , radical , oxidative stress , biology , cell
Iron‐based and indirect iron‐based nanomaterials can be developed for cancer therapy based on ferroptosis via release of their own iron or loaded endogenous iron in lysosomes after endocytosis, which can employ the Fenton reaction to produce reactive oxygen species (ROS) and induce lipid peroxidation. These systems are reviewed by Zijian Zhou, Aiguo Wu, Xiaoyuan Chen, and co‐workers in article number 1704007 .