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Flexible and Implantable Microelectrodes for Chronically Stable Neural Interfaces
Author(s) -
Shi Jidong,
Fang Ying
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201804895
Subject(s) - neuroprosthetics , microelectrode , millisecond , materials science , neural engineering , nanotechnology , brain–computer interface , rigidity (electromagnetism) , neural prosthesis , signal (programming language) , neural activity , neuroscience , biomedical engineering , computer science , electrode , electroencephalography , artificial intelligence , engineering , chemistry , physics , astronomy , composite material , biology , programming language
Implantable electrical probes that can record neural activities at single‐neuron and sub‐millisecond resolution are the most widely applied tools in both neuroscience research and neuroprosthetics. However, the structural and mechanical mismatch between conventional rigid probes and neural tissues results in inflammatory responses and signal degradation over chronic recordings. Reducing the cross‐sectional footprints and rigidity of the probes can effectively improve the long‐term stability of neural interfaces. Herein, recent progress in the development of implantable microelectrodes for chronically stable neural interfaces is highlighted, with a focus on the utilization of advanced materials and structural design concepts.