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Targeting Peptide‐Based Probes for Molecular Imaging and Diagnosis
Author(s) -
Wang Weizhi,
Hu Zhiyuan
Publication year - 2019
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201804827
Subject(s) - materials science , peptide , nanotechnology , molecular imaging , medical imaging , medical physics , medicine , radiology , biochemistry , biology , genetics , in vivo
A series of novel peptide‐based molecular probes for different biomarkers is highlighted herein. These probes can provide targeted recognition with high affinity, high specificity, high penetration, and rapid excretion ability. These sensitive peptides can achieve rapid and specific detection when they are conjugated with imaging moieties or are formed into nanoprobes, which can be adapted for in vivo molecular imaging in targeted diagnosis and therapy.