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Bioelectronics: Electromechanical Nanogenerator–Cell Interaction Modulates Cell Activity (Adv. Mater. 24/2017)
Author(s) -
Murillo Gonzalo,
Blanquer Andreu,
VargasEstevez Carolina,
Barrios Lleonard,
Ibáñez Elena,
Nogués Carme,
Esteve Jaume
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201770166
Subject(s) - bioelectronics , materials science , nanogenerator , nanotechnology , piezoelectricity , stimulation , cell , viability assay , scanning electron microscope , biophysics , microbiology and biotechnology , neuroscience , biology , biosensor , biochemistry , composite material
Saos‐2 cells are cultured on top of piezoelectric nanogenerators (NGs) based on ZnO nanosheets for electrical self‐stimulation by Gonzalo Murillo, Carme Nogués, and co‐workers in article number 1605048 . Imaging by scanning electron microscopy (SEM) shows that the cells are firmly adhered to the nanosheets. The cells show excellent viability, proliferation, and differentiation. The NGs can be used to electrically self‐stimulate different types of cells, such as neurons or muscle cells, without applying a chemical or physical external stimulation, leading to future bioelectronic medicines based on cell‐targeted local electrical impulses.