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Glucose‐Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid
Author(s) -
Yetisen Ali K.,
Jiang Nan,
Fallahi Afsoon,
Montelongo Yunuen,
RuizEsparza Guillermo U.,
Tamayol Ali,
Zhang Yu Shrike,
Mahmood Iram,
Yang SuA,
Kim Ki Su,
Butt Haider,
Khademhosseini Ali,
Yun SeokHyun
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201606380
Subject(s) - phenylboronic acid , materials science , continuous glucose monitoring , ethylene glycol , biomedical engineering , continuous monitoring , optical fiber , lactic acid , boronic acid , nanotechnology , insulin , computer science , glycemic , combinatorial chemistry , chemistry , organic chemistry , catalysis , medicine , telecommunications , operations management , biology , bacteria , economics , genetics , endocrinology
Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide‐ co ‐poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis ‐diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range.