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Host Materials Transformable in Tumor Microenvironment for Homing Theranostics
Author(s) -
Yang PeiPei,
Luo Qiang,
Qi GuoBin,
Gao YuJuan,
Li BingNan,
Zhang JingPing,
Wang Lei,
Wang Hao
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201605869
Subject(s) - homing (biology) , tumor microenvironment , materials science , host (biology) , nanotechnology , nanofiber , tumor cells , cancer research , biology , ecology
A pathology‐adaptive nanosystem , in which nest‐like hosts are built based on nanofibers that are transformed from i.v. injected nanoparticles under the acidic tumor microenvironment. The solid tumor is artificially modified by nest‐like hosts readily and firmly, resulting in highly efficient accumulation and stabilization of guest theranostics. This strategy shows great potential for the theranostics delivery to tumors.