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A Self‐Powered Implantable Drug‐Delivery System Using Biokinetic Energy
Author(s) -
Song Peiyi,
Kuang Shuangyang,
Panwar Nishtha,
Yang Guang,
Tng Danny Jian Hang,
Tjin Swee Chuan,
Ng Wun Jern,
Majid Maszenan Bin Abdul,
Zhu Guang,
Yong KenTye,
Wang Zhong Lin
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201605668
Subject(s) - triboelectric effect , drug delivery , materials science , nanogenerator , ex vivo , biomedical engineering , delivery system , drug , nanotechnology , in vivo , pharmacology , medicine , microbiology and biotechnology , composite material , biology , piezoelectricity
The first triboelectric‐nanogenerator (TENG)‐based self‐powered implantable drug‐delivery system is presented. Pumping flow rates from 5.3 to 40 µL min −1 under different rotating speeds of the TENG are realized. The implantable drug‐delivery system can be powered with a TENG device rotated by human hand motion. Ex vivo trans‐sclera drug delivery in porcine eyes is demonstrated by utilizing the biokinetic energies of human hands.