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Cation Tuning of Supramolecular Gel Properties: A New Paradigm for Sustained Drug Delivery
Author(s) -
Ramin Michael A.,
Sindhu Kotagudda Ranganath,
Appavoo Ananda,
Oumzil Khalid,
Grinstaff Mark W.,
Chassande Olivier,
Barthélémy Philippe
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201605227
Subject(s) - self healing hydrogels , drug delivery , supramolecular chemistry , materials science , biocompatible material , nanotechnology , self assembly , drug , in vivo , combinatorial chemistry , chemical engineering , biomedical engineering , molecule , organic chemistry , polymer chemistry , chemistry , pharmacology , engineering , medicine , microbiology and biotechnology , biology
Hydrogels formed by the self‐assembly of low‐molecular‐weight gelators (LMWGs) are promising scaffolds for drug‐delivery applications. A new biocompatible hydrogel, resulting from the self‐assembly of nucleotide‐lipid salts can be safely injected in vivo. The resulting hydrogel provides sustained‐release of protein for more than a week.