Premium
Metal‐Organic Framework as a Protective Coating for Biodiagnostic Chips
Author(s) -
Wang Congzhou,
Tadepalli Sirimuvva,
Luan Jingyi,
Liu KengKu,
Morrissey Jeremiah J.,
Kharasch Evan D.,
Naik Rajesh R.,
Singamaneni Srikanth
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201604433
Subject(s) - materials science , nanotechnology , metal organic framework , imidazolate , coating , zeolitic imidazolate framework , biochip , metal , chemical engineering , plasmon , nanostructure , optoelectronics , adsorption , metallurgy , organic chemistry , chemistry , engineering
Zeolitic imidazolate framework‐8 (ZIF‐8) grown around antibodies anchored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability of antibodies stored at room and elevated temperatures for several days. The biofunctionality of the ZIF‐8‐protected biochip can be restored by a simple water‐rinsing step, making it highly convenient for use in point‐of‐care and resource‐limited settings.