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Guiding Cell Attachment in 3D Microscaffolds Selectively Functionalized with Two Distinct Adhesion Proteins
Author(s) -
Richter Benjamin,
Hahn Vincent,
Bertels Sarah,
Claus Tanja K.,
Wegener Martin,
Delaittre Guillaume,
BarnerKowollik Christopher,
Bastmeyer Martin
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201604342
Subject(s) - surface modification , nanotechnology , materials science , adhesion , cell , computer science , computational biology , biophysics , biochemistry , chemistry , biology , chemical engineering , engineering , composite material
The combination of three different photoresists into a single direct laser written 3D microscaffold permits functionalization with two bioactive full‐length proteins. The cell‐instructive microscaffolds consist of a passivating framework equipped with light activatable constituents featuring distinct protein‐binding properties. This allows directed cell attachment of epithelial or fibroblast cells in 3D.