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Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus
Author(s) -
Hu Quanyin,
Qian Chenggen,
Sun Wujin,
Wang Jinqiang,
Chen Zhaowei,
Bomba Hunter N.,
Xin Hongliang,
Shen Qundong,
Gu Zhen
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201603463
Subject(s) - nanocarriers , multiple myeloma , materials science , thrombus , nanotechnology , drug delivery , computer science , medicine
A platelet‐membrane‐coated biomimetic nanocarrier , which can sequentially target the bone microenvironment and myeloma cells to enhance the drug availability at the myeloma site and decrease off‐target effects, is developed for inhibiting multiple myeloma growth and simultaneously eradicating thrombus complication.