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Bottom‐Up Structuring and Site‐Selective Modification of Hydrogels Using a Two‐Photon [2+2] Cycloaddition of Maleimide
Author(s) -
Jungnickel Christiane,
Tsurkan Mikhail V.,
Wogan Kristin,
Werner Carsten,
Schlierf Michael
Publication year - 2017
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201603327
Subject(s) - maleimide , self healing hydrogels , cycloaddition , materials science , micrometer , structuring , two photon excitation microscopy , nanotechnology , chemical engineering , polymer chemistry , organic chemistry , chemistry , optics , fluorescence , catalysis , physics , finance , economics , engineering
Creating hydrogel systems to mimic the extracellular matrix is often limited by their static nature. The use of a two‐photon [2+2] cycloaddition of maleimide groups to structure surfaces, to create hydrogels, and add 3D modifications with sub‐micrometer precision is reported. The absence of photoinitiators and usage of near‐infrared light is promising for future in vivo studies.