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Metal–Organic‐Framework‐Derived Mesoporous Carbon Nanospheres Containing Porphyrin‐Like Metal Centers for Conformal Phototherapy
Author(s) -
Wang Shunhao,
Shang Lu,
Li Linlin,
Yu Yingjie,
Chi Chongwei,
Wang Kun,
Zhang Jie,
Shi Run,
Shen Heyun,
Waterhouse Geoffrey I. N.,
Liu Sijin,
Tian Jie,
Zhang Tierui,
Liu Huiyu
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201602197
Subject(s) - porphyrin , materials science , nanotechnology , metal organic framework , imidazolate , mesoporous silica , photothermal therapy , mesoporous material , photoacoustic imaging in biomedicine , pyrolysis , zeolitic imidazolate framework , carbon fibers , photochemistry , adsorption , organic chemistry , catalysis , chemistry , physics , optics , composite number , composite material
Mesoporous carbon nanospheres containing porphyrin‐like metal centers (denoted as “PMCS”) are successfully synthesized by the pyrolysis of an imidazolate framework using a mesoporous‐silica protection strategy. The PMCS allow infrared and photoacoustic imaging and synergetic photothermal therapy/photodynamic therapy derived from the porphyrin‐like moieties, offering the possibility of real‐time monitoring of therapeutic processes and image‐guided precise conformal phototherapy. PMCS thus represent a novel multifunctional theranostic platform for improved treatment efficiencies.