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Ambient Aqueous Synthesis of Ultrasmall PEGylated Cu 2− x Se Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer
Author(s) -
Zhang Shaohua,
Sun Caixia,
Zeng Jianfeng,
Sun Qiao,
Wang Guanglin,
Wang Yong,
Wu Yan,
Dou Shixue,
Gao Mingyuan,
Li Zhen
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201602193
Subject(s) - photothermal therapy , materials science , nanoparticle , nanotechnology , aqueous solution , biocompatible material , photoacoustic imaging in biomedicine , absorption (acoustics) , biomedical engineering , organic chemistry , chemistry , optics , medicine , physics , composite material
Ultrasmall PEGylated Cu 2– x Se nanoparticles with strong near‐infrared absorption have been prepared by an ambient aqueous method. The resultant water‐soluble and biocompatible nanoparticles are demonstrated to be a novel nanotheranostic agent for effective deep‐tissue photoacoustic imaging, computed tomography imaging, single‐photon emission computed tomography imaging, and photothermal therapy of cancer.