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Controllable Self‐Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting
Author(s) -
Li Hui,
Zhang Kaiming,
Pi Fengmei,
Guo Sijin,
Shlyakhtenko Luda,
Chiu Wah,
Shu Dan,
Guo Peixuan
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201601976
Subject(s) - pharmaceutics , pharmacy , pharmaceutical sciences , chemistry , medicine , library science , pharmacology , family medicine , computer science
RNA tetrahedral nanoparticles with two different sizes are successfully assembled by a one‐pot bottom‐up approach with high efficiency and thermal stability. The reported design principles can be extended to construct higher‐order polyhedral RNA architectures for various applications such as targeted cancer imaging and therapy.