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An Injectable Self‐Assembling Collagen–Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy
Author(s) -
Xing Ruirui,
Liu Kai,
Jiao Tifeng,
Zhang Ning,
Ma Kai,
Zhang Ruiyun,
Zou Qianli,
Ma Guanghui,
Yan Xuehai
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201600284
Subject(s) - photothermal therapy , materials science , self healing hydrogels , biomineralization , photodynamic therapy , self healing , nanotechnology , biomedical engineering , chemical engineering , polymer chemistry , medicine , chemistry , pathology , alternative medicine , organic chemistry , engineering
An injectable and self‐healing collagen–gold hybrid hydrogel is spontaneously formed by electrostatic self‐assembly and subsequent biomineralization. It is demonstrated that such collagen‐based hydrogels may be used as an injectable material for local delivery of therapeutic agents, showing enhanced antitumor efficacy.