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Quantitative Probing of Cu 2+ Ions Naturally Present in Single Living Cells
Author(s) -
Lee Junho,
Lee HwaRim,
Pyo Jaeyeon,
Jung Youngseob,
Seo JiYoung,
Ryu Hye Guk,
Kim KyongTai,
Je Jung Ho
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201600161
Subject(s) - ion , nanowire , quenching (fluorescence) , materials science , intracellular , photoluminescence , nanotechnology , quantum dot , analytical chemistry (journal) , optoelectronics , fluorescence , physics , chemistry , biochemistry , environmental chemistry , quantum mechanics
Quantitative probing of Cu 2+ ions naturally present in single living cells is realized by developing a quantum‐dot‐embedded nanowire‐waveguide probe. The intracellular Cu 2+ ion concentration is quantified by direct monitoring of photoluminescence quenching during the insertion of the nanowire in a living neuron. The measured intracellular Cu 2+ ion concentration is 3.34 ± 1.04 × 10 −6 m (mean ± s.e.m.) in single hippocampal neurons.
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