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Nanoparticles: A Prussian Blue‐Based Core–Shell Hollow‐Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH‐Responsive Longitudinal Relaxivity (Adv. Mater. 41/2015)
Author(s) -
Cai Xiaojun,
Gao Wei,
Ma Ming,
Wu Meiying,
Zhang Linlin,
Zheng Yuanyi,
Chen Hangrong,
Shi Jianlin
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201570281
Subject(s) - prussian blue , materials science , nanoparticle , mesoporous material , nanotechnology , mesoporous silica , chemical engineering , electrode , organic chemistry , chemistry , electrochemistry , catalysis , engineering
A novel core‐shell hollow‐structured HMPB‐Mn (HMPBs = hollow mesoporous Prussian blue nanoparticles) as an intelligent theranostic nanoagent, is successfully constructed by H. Chen, J. Shi, and co‐workers as described on page 6382. This is achieved by coating a similarly crystal‐structured Mn‐containing Prussian blue analogue onto hollow‐structured mesoporous Prussian blue nanoparticles. These can be used as pH‐responsive T 1 ‐weighted magnetic resonance imaging (MRI) contrast agents (CAs) with ultrahigh longitudinal relaxivity, and achieve the real‐time monitoring of drug release.