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Membranes: Transparent, Nanoporous, and Transferable Membrane‐Based Cell–Cell Paracrine Signaling Assay (Adv. Mater. 11/2015)
Author(s) -
Jang Yeongseon,
Lee Hyojin,
Char Kookheon,
Nam JwaMin
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201570073
Subject(s) - paracrine signalling , materials science , stromal cell , nanoporous , membrane , microbiology and biotechnology , nanotechnology , biophysics , chemistry , biology , cancer research , biochemistry , receptor
A transparent, nanoporous, and transferable (TNT) membrane‐based cell co‐culture platform is developed by K. Char, J.‐M. Nam, and co‐workers on page 1893 for systematic investigation and control of paracrine signaling between cancerous and stromal cells. With the high degree of freedom in tuning nanopores, analyzing cells of interest, and manipulating the TNT membranes, the paracrine signaling between metastatic cancer cells and three different types of stromal cells is studied and controlled.