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Hierarchical Plasmonic Nanorods and Upconversion Core–Satellite Nanoassemblies for Multimodal Imaging‐Guided Combination Phototherapy
Author(s) -
Sun Maozhong,
Xu Liguang,
Ma Wei,
Wu Xiaoling,
Kuang Hua,
Wang Libing,
Xu Chuanlai
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201505023
Subject(s) - nanorod , photon upconversion , photothermal therapy , materials science , nanotechnology , plasmon , satellite , surface plasmon resonance , core (optical fiber) , nanoparticle , computer science , optoelectronics , luminescence , physics , composite material , astronomy
DNA‐driven hierarchical core–satellite nanostructures with plasmonic gold nanorod dimers and upconversion nanoparticles are fabricated. Once the core–satellite structure is activated, combined photothermal therapy and photodynamic therapy are carried out under the guidance of upconversion luminesce, T 1 ‐weighted magnetic resonance, photoacoustics, and computed tomography imaging of tumors in vivo, which exhibit the multifunctional biological applications of the DNA‐based self‐assemblies.