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Design of Enzyme‐Encapsulated Protein Containers by In Vivo Crystal Engineering
Author(s) -
Abe Satoshi,
Ijiri Hiroshi,
Negishi Hashiru,
Yamanaka Hiroyuki,
Sasaki Katsuhito,
Hirata Kunio,
Mori Hajime,
Ueno Takafumi
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201503827
Subject(s) - enzyme , materials science , dissolution , in vivo , crystal (programming language) , protein crystallization , protein engineering , crystal engineering , nanotechnology , chemical engineering , crystal structure , biochemistry , crystallography , chemistry , organic chemistry , crystallization , biology , computer science , microbiology and biotechnology , supramolecular chemistry , programming language , engineering
Crystalline protein assemblies of polyhedra crystal (PhC) can be utilized as solid enzyme containers for long‐term storage of enzymes with retention of their enzymatic activity. The enzymes can be released from the crystals at the optimum pH for the enzymatic activity by dissolution of the crystals using in vivo crystal engineering.