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Biodegradable‐Polymer‐Blend‐Based Surgical Sealant with Body‐Temperature‐Mediated Adhesion
Author(s) -
Behrens Adam M.,
Lee Nora G.,
Casey Brendan J.,
Srinivasan Priya,
Sikorski Michael J.,
Daristotle John L.,
Sandler Anthony D.,
Kofinas Peter
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201503691
Subject(s) - library science , medicine , management , engineering , economics , computer science
The development of practical and efficient surgical sealants has the propensity to improve operational outcomes. A biodegradable polymer blend is fabricated as a nonwoven fiber mat in situ. After direct deposition onto the tissue of interest, the material transitions from a fiber mat to a film. This transition promotes polymer–substrate interfacial interactions leading to improved adhesion and surgical sealant performance.