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Pathological‐Condition‐Driven Construction of Supramolecular Nanoassemblies for Bacterial Infection Detection
Author(s) -
Li LiLi,
Ma HuaiLei,
Qi GuoBin,
Zhang Di,
Yu Faquan,
Hu Zhiyuan,
Wang Hao
Publication year - 2016
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201503437
Subject(s) - materials science , supramolecular chemistry , nanotechnology , organic chemistry , molecule , chemistry
A pyropheophorbide‐α‐based building block (Ppa‐PLGVRG‐Van) can be used to construct self‐aggregated superstructures in vivo for highly specific and sensitive diagnosis of bacterial infection by noninvasive photoacoustic tomography. This in vivo supramolecular chemistry approach opens a new avenue for efficient, rapid, and early‐stage disease diagnosis with high sensitivity and specificity.