A Prussian Blue‐Based Core–Shell Hollow‐Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH‐Responsive Longitudinal Relaxivity | Zendy

Cai Xiaojun | Zendy; Gao Wei | Zendy; Ma Ming | Zendy; Wu Meiying | Zendy; Zhang Linlin | Zendy; Zheng Yuanyi | Zendy; Chen Hangrong | Zendy; Shi Jianlin | Zendy

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A Prussian Blue‐Based Core–Shell Hollow‐Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH‐Responsive Longitudinal Relaxivity

Author(s) -

Cai Xiaojun,

Gao Wei,

Ma Ming,

Wu Meiying,

Zhang Linlin,

Zheng Yuanyi,

Chen Hangrong,

Shi Jianlin

Publication year - 2015

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201503381

Subject(s) - prussian blue , materials science , nanoparticle , mesoporous material , nanotechnology , chemical engineering , organic chemistry , electrode , chemistry , engineering , electrochemistry , catalysis

Novel core–shell hollow mesoporous Prussian blue @ Mn‐containing Prussian blue analogue (HMPB@MnPBA) nanoparticles, designated as HMPB‐Mn) as an intelligent theranostic nanoagent, are successfully constructed by coating a similarly crystal‐structured MnPBA onto HMPB. This can be used as a pH‐responsive T 1 ‐weighted magnetic resonance imaging contrast agent with ultrahigh longitudinal relaxivity ( r 1 = 7.43 m m −1 s −1 ), and achieves the real‐time monitoring of drug release.

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