Premium
Spatially, Temporally, and Quantitatively Controlled Delivery of Broad Range of Molecules into Selected Cells through Plasmonic Nanotubes
Author(s) -
Messina Gabriele C.,
Dipalo Michele,
La Rocca Rosanna,
Zilio Pierfrancesco,
Caprettini Valeria,
Proietti Zaccaria Remo,
Toma Andrea,
Tantussi Francesco,
Berdondini Luca,
De Angelis Francesco
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201503252
Subject(s) - materials science , plasmon , microfluidics , nanotechnology , molecule , intracellular , extracellular , transfection , biophysics , optoelectronics , chemistry , biology , cell culture , biochemistry , organic chemistry , genetics
A Universal plasmonic/microfluidic platform for spatial and temporal controlled intracellular delivery is described. The system can inject/transfect the desired amount of molecules with an efficacy close to 100%. Moreover, it is highly scalable from single cells to large ensembles without administering the molecules to an extracellular bath. The latter enables quantitative control over the amount of injected molecules.