An Optical Nanoruler Based on a Conjugated Polymer−Silver Nanoprism Pair for Label‐Free Protein Detection | Zendy

Wang Xiaoyu | Zendy; Li Shengliang | Zendy; Zhang Pengbo | Zendy; Lv Fengting | Zendy; Liu Libing | Zendy; Li Lidong | Zendy; Wang Shu | Zendy

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An Optical Nanoruler Based on a Conjugated Polymer−Silver Nanoprism Pair for Label‐Free Protein Detection

Author(s) -

Wang Xiaoyu,

Li Shengliang,

Zhang Pengbo,

Lv Fengting,

Liu Libing,

Li Lidong,

Wang Shu

Publication year - 2015

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201502880

Subject(s) - materials science , conjugated system , polymer , nanotechnology , optoelectronics , composite material

An optical nanoruler system based on a conjugated polyelectrolyte−silver nanoprism pair is developed for label‐free protein detection by taking advantage of the metal‐enhanced fluorescence effect of silver nanostructures. Antibody–antigen interactions induce a change in the metal–fluorophore distance, followed by the response of a fluorescent signal of the conjugated polyelectrolyte. The system is used to detect target antigens sensitively and selectively.

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