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Large‐Scale Nanoelectrode Arrays to Monitor the Dopaminergic Differentiation of Human Neural Stem Cells
Author(s) -
Kim TaeHyung,
Yea CheolHeon,
Chueng SyTsong Dean,
Yin Perry ToTien,
Conley Brian,
Dardir Kholud,
Pak Yusin,
Jung Gun Young,
Choi JeongWoo,
Lee KiBum
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201502489
Subject(s) - nanotechnology , materials science , computer science , lithography , stem cell , scale (ratio) , regenerative medicine , neuroscience , biology , optoelectronics , microbiology and biotechnology , physics , quantum mechanics
A novel cell‐based biosensing platform is developed using a combination of sequential laser interference lithography and electrochemical deposition methods. This enables the sensitive discrimination of dopaminergic cells from other types of neural cells in a completely nondestructive manner. This platform and detection strategy may become an effective noninvasive in situ monitoring tool that can be used to determine stem cell fate for various regenerative applications.