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Core–Shell Upconversion Nanoparticle@Metal–Organic Framework Nanoprobes for Luminescent/Magnetic Dual‐Mode Targeted Imaging
Author(s) -
Li Yantao,
Tang Jinglong,
He Liangcan,
Liu Yong,
Liu Yaling,
Chen Chunying,
Tang Zhiyong
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201501779
Subject(s) - materials science , nanoparticle , luminescence , metal organic framework , nanotechnology , nanostructure , photon upconversion , dual mode , surface modification , coating , shell (structure) , optoelectronics , chemical engineering , composite material , organic chemistry , chemistry , adsorption , aerospace engineering , engineering
Core–shell upconversion nanoparticle@metal–organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF 4 :Yb,Er nanoparticle (NP) cores with amino‐functionalized iron carboxylate MOF shells. These nanostructures combine the near‐infrared optical property of the UCNP cores and the T 2 ‐magnetic response (MR) imaging property of the MOF shells. After surface modification, the core–shell nanostructures are demonstrated as high‐resolution nanoprobes for targeted luminescence/MR imaging both in vitro and in vivo.