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Theranostic Gold Nanomicelles made from Biocompatible Comb‐like Polymers for Thermochemotherapy and Multifunctional Imaging with Rapid Clearance
Author(s) -
Deng Heng,
Dai Fengying,
Ma Guanghui,
Zhang Xin
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201501420
Subject(s) - materials science , biocompatible material , nanotechnology , polymer , biomedical engineering , composite material , medicine
A new generation of photothermal theranostic agent s based on assembling 6 nm gold nanoparticles (AuNPs) is developed by using a novel comb‐like amphipathic polymer as the template. The small AuNPs are assembled into DOX@gold nanomicelles, which show strong absorbance in the near‐infrared region, for multimodal bioimaging and highly effective in vivo chemotherapy and photothermal therapy.