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Controlling Epileptiform Activity with Organic Electronic Ion Pumps
Author(s) -
Williamson Adam,
Rivnay Jonathan,
Kergoat Loïg,
Jonsson Amanda,
Inal Sahika,
Uguz Ilke,
Ferro Marc,
Ivanov Anton,
Sjöström Theresia Arbring,
Simon Daniel T.,
Berggren Magnus,
Malliaras George G.,
Bernard Christophe
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201500482
Subject(s) - materials science , ion pump , epilepsy , organic molecules , neuroscience , electrophysiology , electroencephalography , nanotechnology , ion , molecule , biology , organic chemistry , chemistry
In treating epilepsy , the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on‐demand pure molecules to specific brain regions. State‐of‐the‐art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified with electrophysiological recordings.