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Meter‐Long Multiblock Copolymer Microfibers Via Interfacial Bioorthogonal Polymerization
Author(s) -
Liu Shuang,
Zhang Han,
Remy Roddel A.,
Deng Fei,
Mackay Michael E.,
Fox Joseph M.,
Jia Xinqiao
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201500360
Subject(s) - bioorthogonal chemistry , copolymer , materials science , polymerization , monomer , polymer , polymer science , tetrazine , nanotechnology , polymer chemistry , click chemistry , organic chemistry , chemistry , composite material
High‐molecular‐weight multiblock copolymers are synthesized as robust polymer fibers via interfacial bioorthogonal polymerization employing the rapid cycloaddition of s ‐tetrazines with strained trans ‐cyclooctenes. When cell‐adhesive peptide is incorporated in the tetrazine monomer, the resulting protein‐mimetic polymer fibers provide guidance cues for cell attachment and elongation.