Nanomedicine: Break‐up of Two‐Dimensional MnO 2  Nanosheets Promotes Ultrasensitive pH‐Triggered Theranostics of Cancer (Adv. Mater. 41/2014) | Zendy

Chen Yu | Zendy; Ye Delai | Zendy; Wu Meiying | Zendy; Chen Hangrong | Zendy; Zhang Linlin | Zendy; Shi Jianlin | Zendy; Wang Lianzhou | Zendy

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Nanomedicine: Break‐up of Two‐Dimensional MnO 2 Nanosheets Promotes Ultrasensitive pH‐Triggered Theranostics of Cancer (Adv. Mater. 41/2014)

Author(s) -

Chen Yu,

Ye Delai,

Wu Meiying,

Chen Hangrong,

Zhang Linlin,

Shi Jianlin,

Wang Lianzhou

Publication year - 2014

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201470284

Subject(s) - nanomedicine , materials science , nanotechnology , in vivo , in vitro , cancer , tumor microenvironment , cancer research , biophysics , nanoparticle , tumor cells , chemistry , biochemistry , medicine , biology , microbiology and biotechnology

Exfoliated 2D MnO 2 nanosheets described by J. Shi, L. Wang, and co‐workers on page 7019, show a unique break‐up nature in mild acidic microenvironment of tumor tissues, which could substantially enhance the in vitro and in vivo performances of T 1 ‐weighted magnetic resonance imaging. Such a pH‐triggered break‐up nature can also promote the fast release of loaded anticancer drugs for concurrent pH‐responsive theranostics of cancer.

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