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Imaging: Upconversion Nanoparticles as a Contrast Agent for Photoacoustic Imaging in Live Mice (Adv. Mater. 32/2014)
Author(s) -
Maji Swarup Kumar,
Sreejith Sivaramapanicker,
Joseph James,
Lin Manjing,
He Tingchao,
Tong Yan,
Sun Handong,
Yu Sidney WingKwong,
Zhao Yanli
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201470220
Subject(s) - materials science , photoacoustic imaging in biomedicine , photon upconversion , nanoparticle , excited state , photoacoustic effect , in vivo , relaxation (psychology) , quenching (fluorescence) , photoacoustic spectroscopy , luminescence , optoelectronics , nanotechnology , optics , fluorescence , psychology , social psychology , physics , microbiology and biotechnology , nuclear physics , biology
Photoacoustic imaging has evolved as a promising deep‐tissue optical imaging modality. On page 5633, Y. Zhao and co‐workers demonstrate the inclusion complex of NaYF 4 :Yb 3+ ,Er 3+ upconversion nanoparticles with α‐cyclodextrin in aqueous conditions that exhibits luminescence quenching when excited at 980 nm. This non‐radiative relaxation leads to photoacoustic signal enhancement in vivo, showing high capability of the material for photoacoustic imaging.