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Nanodots: Ultrasmall NaGdF 4 Nanodots for Efficient MR Angiography and Atherosclerotic Plaque Imaging (Adv. Mater. 23/2014)
Author(s) -
Xing Huaiyong,
Zhang Shengjian,
Bu Wenbo,
Zheng Xiangpeng,
Wang Lijun,
Xiao Qingfeng,
Ni Dalong,
Zhang Jiamin,
Zhou Liangping,
Peng Weijun,
Zhao Kuaile,
Hua Yanqing,
Shi Jianlin
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201470157
Subject(s) - nanodot , materials science , magnetic resonance imaging , lumen (anatomy) , magnetic resonance angiography , angiography , nuclear magnetic resonance , radiology , nanotechnology , medicine , physics , surgery
As shown by J. Shi, W. Bu, and co‐workers on page 3867, ultrasmall NaGdF 4 nanodots (ca. 2 nm) with diethylenetriaminepenta‐acetic acid (DTPA) conjugation are synthesized for efficient magnetic resonance (MR) angiography. Impressively, the r 1 value in magnetic resonance imaging (MRI) reaches up to 8.93 mM −1 s −1 . The ultrasmall vessel lumen of a rabbit is lit up remarkably. After 3 h, atherosclerotic plaques can be discriminated clearly. This is quite favorable for the accurate early diagnosis of vascular pathema.