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Biomedical Applications: Endocytic pH‐Triggered Degradation of Nanoengineered Multilayer Capsules (Adv. Mater. 12/2014)
Author(s) -
Liang Kang,
Such Georgina K.,
Johnston Angus P. R.,
Zhu Zhiyuan,
Ejima Hirotaka,
Richardson Joseph J.,
Cui Jiwei,
Caruso Frank
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201470080
Subject(s) - materials science , nanotechnology , endocytic cycle , degradation (telecommunications) , layer (electronics) , drug delivery , chemistry , endocytosis , computer science , biochemistry , telecommunications , cell
Smart delivery systems with inbuilt biological triggers are emerging for advanced therapeutic delivery applications. F. Caruso and co‐workers describe on page 1901 the synthesis of crosslinker‐free, layer‐by‐layer (LbL) capsules that utilize cellular pH variations as a trigger to specifically deconstruct and subsequently release cargo in cells.