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Co 9 Se 8 Nanoplates as a New Theranostic Platform for Photoacoustic/Magnetic Resonance Dual‐Modal‐Imaging‐Guided Chemo‐Photothermal Combination Therapy
Author(s) -
Song XiaoRong,
Wang Xiaoyong,
Yu ShuXian,
Cao Jianbo,
Li ShiHua,
Li Juan,
Liu Gang,
Yang HuangHao,
Chen Xiaoyuan
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201405634
Subject(s) - photothermal therapy , photoacoustic imaging in biomedicine , materials science , nanotechnology , magnetic resonance imaging , biocompatible material , biomedical engineering , optics , radiology , medicine , physics
A new theranostic platform is developed based on biocompatible poly(acrylic acid) (PAA)‐Co 9 Se 8 nanoplates. These PAA‐Co 9 Se 8 nanoplates are successfully utilized for photoacoustic imaging (PAI)/magnetic resonance imaging (MRI) dual‐modal imaging. Moreover, the PAA‐Co 9 Se 8 ‐DOX shows pH‐responsive chemotherapy and enables the combination of photothermal therapy and chemotherapy to receive superior antitumor efficacy. This work promises further exploration of 2D nanoplatforms for theranostic applications.