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One Step Creation of Multifunctional 3D Architectured Hydrogels Inducing Bone Regeneration
Author(s) -
Neffe Axel T.,
Pierce Benjamin F.,
Tronci Giuseppe,
Ma Nan,
Pittermann Erik,
Gebauer Tim,
Frank Oliver,
Schossig Michael,
Xu Xun,
Willie Bettina M.,
Forner Michèle,
Ellinghaus Agnes,
Lienau Jasmin,
Duda Georg N.,
Lendlein Andreas
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201404787
Subject(s) - materials science , self healing hydrogels , biomaterial , regeneration (biology) , adhesion , cell adhesion , nanotechnology , in vivo , biomedical engineering , biophysics , composite material , microbiology and biotechnology , polymer chemistry , biology , medicine
Structured hydrogels showing form stability and elastic properties individually tailorable on different length scales are accessible in a one‐step process. They support cell adhesion and differentiation and display growing pore size during degradation. In vivo experiments demonstrate their efficacy in biomaterial‐induced bone regeneration, not requiring addition of cells or growth factors.