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pH‐Stimulated DNA Hydrogels Exhibiting Shape‐Memory Properties
Author(s) -
Guo Weiwei,
Lu ChunHua,
Orbach Ron,
Wang Fuan,
Qi XiuJuan,
Cecconello Alessandro,
Seliktar Dror,
Willner Itamar
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201403702
Subject(s) - self healing hydrogels , nucleic acid , materials science , duplex (building) , shape memory alloy , dna , polyacrylamide , chemical engineering , polymer chemistry , composite material , chemistry , biochemistry , engineering
Nucleic acid‐functionalized polyacrylamide chains that are cooperatively cross‐linked by i‐motif and nucleic acid duplex units yield, at pH 5.0, DNA hydrogels exhibiting shape‐memory properties. Separation of the i‐motif units at pH 8.0 dissolves the hydrogel into a quasi‐liquid phase. The residual duplex units provide, however, a memory code in the quasi‐liquid allowing the regeneration of the hydrogel shape at pH 5.0.